Monday, 16 November 2009

Eloxatin


Eloxatin is a brand name of oxaliplatin, approved by the FDA in the following formulation(s):


ELOXATIN (oxaliplatin - injectable; iv (infusion))



  • Manufacturer: SANOFI AVENTIS US

    Approval date: January 31, 2005

    Strength(s): 100MG/20ML (5MG/ML) [RLD][AP], 50MG/10ML (5MG/ML) [RLD][AP]


  • Manufacturer: SANOFI AVENTIS US

    Approval date: November 17, 2006

    Strength(s): 200MG/40ML (5MG/ML) [RLD]

Has a generic version of Eloxatin been approved?


A generic version of Eloxatin has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available - possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Eloxatin and have been approved by the FDA:


oxaliplatin injectable; iv (infusion)



  • Manufacturer: EBEWE PHARMA

    Approval date: August 7, 2009

    Strength(s): 100MG/20ML (5MG/ML) [AP], 50MG/10ML (5MG/ML) [AP]


  • Manufacturer: FRESENIUS KABI ONCOL

    Approval date: June 10, 2010

    Strength(s): 100MG/20ML (5MG/ML) [AP], 50MG/10ML (5MG/ML) [AP]


  • Manufacturer: HOSPIRA WORLDWIDE

    Approval date: August 7, 2009

    Strength(s): 100MG/20ML (5MG/ML) [AP], 50MG/10ML (5MG/ML) [AP]


  • Manufacturer: SANDOZ

    Approval date: January 24, 2011

    Strength(s): 100MG/20ML (5MG/ML) [AP], 50MG/10ML (5MG/ML) [AP]


  • Manufacturer: TEVA PARENTERAL

    Approval date: August 7, 2009

    Strength(s): 100MG/20ML (5MG/ML) [AP], 50MG/10ML (5MG/ML) [AP]

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Eloxatin. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Platinum compound and process of preparing same
    Patent 5,290,961
    Issued: March 1, 1994
    Inventor(s): Okamoto; Koji & Hoshi; Yuko & Nakanishi; Chihiro
    Assignee(s): Tanaka Kikinzoku Kogyo K.K.
    Disclosed herein are a platinum compound employed as raw material of medicines having carcinostatic effects, and a process of preparing the platinum compound. The platinum compound (I) substantially free from impurities can be prepared through a reaction between the corresponding dihalogen compound and an organic dibasic acid employing an iodine compound utilizing the difference of solubilities between the desired compound and the iodine compounds.
    Patent expiration dates:

    • January 12, 2013
      ✓ 
      Drug substance


    • July 12, 2013
      ✓ 
      Pediatric exclusivity




  • Cis oxalato (trans 1-1,2-cyclohexanediamine) PT(II) having optically high purity
    Patent 5,338,874
    Issued: August 16, 1994
    Inventor(s): Nakanishi; Chihiro & Ohnishi; Yuko & Ohnishi; Junji & Taniuchi; Junichi & Okamoto; Koji & Tozawa; Takeshi
    Assignee(s): Tanaka Kikinzoku Kogyo K.K.
    Disclosed herein is cis-oxalato (trans-1-1,2-cyclohexanediamine) Pt(II) optically high purity. Because of its complete optical purity, the compound is effective as raw material of such a medicine as a carcinostatic agent. The complete optical purity of the above compound may be proved by comparing the respective melting points of the cis-oxalato (trans-1-1,2-cyclohexanediamine).
    Patent expiration dates:

    • April 7, 2013
      ✓ 
      Drug substance


    • October 7, 2013
      ✓ 
      Pediatric exclusivity




  • Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same
    Patent 5,420,319
    Issued: May 30, 1995
    Inventor(s): Okamoto; Koji & Nakanishi; Chihiro & Taniuchi; Junichi & Ohnishi; Junji & Komoda; Yasunobu
    Assignee(s): Tanaka Kikinzoku Kogyo K.K.
    Disclosed is cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and no toxicity and exhibiting anticancer performance, as shown in the below Formula. Cis-oxalato(trans-1-1,2-cyclohexanediamine) Pt(II) complex of the invention possesses high optical purity or 99.94% or more e.e. and a melting point of 198.3.degree. to 199.7.degree. C. The complex is synthesized employing as starting material trans-1-1,2-cyclohexamediamine or a derivative of the trans-1-1,2-cyclohexanediamine optically resoluted by means of a high performance liquid chromatography. ##STR1##
    Patent expiration dates:

    • August 9, 2016
      ✓ 
      Drug substance


    • February 9, 2017
      ✓ 
      Pediatric exclusivity




  • Pharmaceutically stable preparation of oxaliplatinum
    Patent 5,716,988
    Issued: February 10, 1998
    Inventor(s): Ibrahim; Houssam & Mauvernay; Rolland-Yves
    Assignee(s): Debiopharm S.A.
    A pharmaceutically stable oxaliplatinum preparation for parenteral administration comprises an aqueous solution of oxaliplatinum, in a concentration of 1 to 5 mg/ml, and with a pH in the range of 4.5 to 6. The aqueous oxaliplatinum solution is advantageously provided as a ready-to-use preparation in a sealed container.
    Patent expiration dates:

    • August 7, 2015
      ✓ 
      Drug product


    • February 7, 2016
      ✓ 
      Pediatric exclusivity



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • July 10, 2010 - PEDIATRIC EXCLUSIVITY

See also...

  • Eloxatin Consumer Information (Drugs.com)
  • Eloxatin Consumer Information (Wolters Kluwer)
  • Eloxatin Consumer Information (Cerner Multum)
  • Eloxatin Advanced Consumer Information (Micromedex)
  • Eloxatin AHFS DI Monographs (ASHP)
  • Oxaliplatin Consumer Information (Wolters Kluwer)
  • Oxaliplatin Consumer Information (Cerner Multum)
  • Oxaliplatin Intravenous Advanced Consumer Information (Micromedex)
  • Oxaliplatin AHFS DI Monographs (ASHP)

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