Maxidex Ophthalmic Ointment

Generic Name: dexamethasone sodium phosphate

Dosage Form: ophthalmic ointment

Maxidex Ophthalmic Ointment Description

MAXIDEX®(Dexamethasone Sodium Phosphate) is an adrenocortical steroid prepared as a sterile ophthalmic ointment. The active ingredient is represented by the chemical structure:

Established name:

Dexamethasone Sodium Phosphate

Chemical name:

Pregn-4-ene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonoxy)-, disodium salt, (11β,16α)-.

Each gram contains: Active: Dexamethasone Sodium Phosphate equivalent to Dexamethasone Phosphate 0.5 mg (0.05%) Inactive: Mineral Oil.

White Petrolatum.                                                      DM - 00

Maxidex Ophthalmic Ointment - Clinical Pharmacology

Dexamethasone sodium phosphate suppresses the inflammatory response to a variety of agents and it probably delays or slows healing. No generally accepted explanation of these steroid properties has been advanced.

INDCIATIONS AND USAGE

Steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe. These include allergic conjunctivitis, acne rosacea, superficial punctate keratits, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivities when the inherent hazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation; corneal injury from chemical or thermal burns, or penetration of foreign bodies.

CONTRAININDICATIONS

Contraindicated in epithelial herpes simplex keratitis (dendritic keratitis); fungal diseases of ocular structures; acute infectious stages of vaccinia, varicella and many other viral disease of the cornea and conjunctiva; mycobacterial infection of the eye and in those persons who have shown hypersensitivity to any component of this preparation.

Warnings

Prolonged use may result in ocular hypertension and/or glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. Prolonged use may suppress the host response an thus increase the hazard of secondary ocular infections. In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical corticosteroids. In acute purulent conditions of the eye, corticosteroids may mask infection or enhance existing infection. If these products are used for 10 days or longer, intraocular pressure should be routinely monitored even though it may be difficult in children and uncooperative patients. Employment of corticosteroid medication in the treatment of herpes simplex other than epithelial herpes simplex keratitis, in which it is contraindicated, requires great caution; periodic slit-lamp microscopy is essential.

Precautions

General

The possibility of persistent fungal infections of the cornea should be considered after prolonged corticosteroid dosing.

Information for Patients

Do not touch tube tip to any surface, as this may contaminate the contents.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Long-term animal studies have not been performed to evaluate the carcinogenic potential or the effect on fertility of MAXIDEX® Ointment.

Pregnancy

Pregnancy Category C. Dexamethasone has been shown to be teratogenic in mice and rabbits following topical ophthalmic application in multiples of the therapeutic dose.

In the mouse, corticosteroids produce fetal resorptions and a specific abnormality, cleft palate. In the rabbit, corticosteroids have produced fetal resorptions and multiple abnormalities involving the head, ears, limbs, palate, etc.

There are no adequate or well-controlled studies in pregnant women. MAXIDEX Ointment should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the embryo or fetus. Infants born of mothers who have received substantial doses of corticosteroids during pregnancy should be observed carefully for signs of hypoadrenalism.

Nursing Mothers

Topically applied steroids are absorbed systemically. Therefore, because of the potential for serious adverse reactions in nursing infants from dexamethasone sodium phosphate, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

Pediatric Use

Safety and effectiveness in children have not been established.

Adverse Reactions

The following adverse reactions have been reported: glaucoma with optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, secondary ocular infections from pathogens including herpes simplex, and perforation of the globe. Rarely, filtering blebs have been reported when topical steroids have been used following cataract surgery. Rarely, stinging or burning may occur.

DOSAGE AND ADMINSTRATION

The duration of treatment will vary with the type of lesion and may extend from a few days to several weeks, according to therapeutic response. Relapses, more common in chronic active lesions than in self-limited conditions, usually respond to treatment. Apply a one-half to one inch ribbon of ointment into the conjunctival sac(s) up to four times daily. When a favorable response is observed, dosage may be reduced gradually to once a day application for several days. MAXIDEX Ointment may be used in conjunction with MAXIDEX suspension.

HOW TO APPLY MAXIDEX OINTMENT

1. Tilt your head back.


2. Place a finger on your cheek just under your eye and gently pull down until a “V” pocket is formed between your eyeball and your lower lid.


3. Place a small amount (about ½ inch) of MAXIDEX in the “V” pocket. Do not let the tip of the tube touch your eye.


4. Look downward before closing your eye.

How is Maxidex Ophthalmic Ointment Supplied

In 3.5g ophthalmic tubes.

NDC 0065-0616-35

STORAGE

Store at 8° - 27°C (46° to 80°F).

CAUTION: Federal (USA) law prohibits dispensing without prescription.

ALCON®

Ophthalmic

Alcon Laboratories, Inc.

Fort Worth, Texas  76134

MAXIDEX  dexamethasone sodium phosphate  ointment

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0065-0616 Route of Administration OPHTHALMIC DEA Schedule

INGREDIENTS Name (Active Moiety) Type Strength dexamethasone sodium phosphate (dexamethasone phosphate) Active 0.5 MILLIGRAM  In 1 GRAM mineral oil Inactive   white petrolatum Inactive

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 0065-0616-35 3.5 g (GRAM) In 1 TUBE None

Revised: 12/2006Alcon

More Maxidex Ophthalmic Ointment resources

• Maxidex Ophthalmic Ointment Use in Pregnancy & Breastfeeding
• Maxidex Ophthalmic Ointment Drug Interactions
• Maxidex Ophthalmic Ointment Support Group
• 0 Reviews for Maxidex Ophthalmic - Add your own review/rating

Compare Maxidex Ophthalmic Ointment with other medications

• Acute Otitis Externa
• Conjunctivitis
• Cyclitis
• Iritis
• Keratitis
• Macular Edema
• Uveitis
• Uveitis, Posterior

Contac 12 Hour Allergy

Generic Name: clemastine (CLEM as teen)

Brand Names: Allerhist-1, Contac 12 Hour Allergy, Tavist, Tavist-1

What is Contac 12 Hour Allergy (clemastine)?

Clemastine is an antihistamine. Clemastine blocks the effects of the naturally occurring chemical histamine in your body.

Clemastine is used to treat sneezing, runny nose, itching watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.

Clemastine is may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Contac 12 Hour Allergy (clemastine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Clemastine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking clemastine.

Who should not take Contac 12 Hour Allergy (clemastine)?

Do not take clemastine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• 
  

  glaucoma or increased pressure in the eye;

  
  


• 
  

  a stomach ulcer;

  
  


• 
  

  an enlarged prostate, bladder problems, or difficulty urinating;

  
  


• 
  

  an overactive thyroid (hyperthyroidism);

  
  


• 
  

  hypertension or any type of heart problems; or

  
  


• 
  

  asthma.

  
  

You may not be able to take clemastine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Clemastine is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take clemastine without first talking to your doctor if you are pregnant. Clemastine passes into breast milk. Infants are especially sensitive to the effects of antihistamines, and serious side effects could occur in a nursing baby. Clemastine is not recommended if you are breast-feeding a baby. Do not take clemastine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from clemastine. You may require a lower dose of this medication.

How should I take Contac 12 Hour Allergy (clemastine)?

Take clemastine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Clemastine can be taken with or without food.

To ensure that you get a correct dose, measure the syrup form of clemastine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of clemastine that you should take in 1 day is 8.04 mg.

Store clemastine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a clemastine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Contac 12 Hour Allergy (clemastine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Clemastine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking clemastine.

Contac 12 Hour Allergy (clemastine) side effects

Stop taking clemastine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take clemastine and talk to your doctor if you experience

• 
  

  sleepiness, fatigue, or dizziness;

  
  


• 
  

  headache;

  
  


• 
  

  dry mouth; or

  
  


• 
  

  difficulty urinating or an enlarged prostate.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Contac 12 Hour Allergy (clemastine)?

Do not take clemastine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These may contain medicines similar to clemastine, which could lead to an overdose of antihistamine.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

• 
  

  anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

  
  


• 
  

  medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

  
  


• 
  

  any other medications that make you feel drowsy, sleepy, or relaxed.

  
  

Drugs other than those listed here may also interact with clemastine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More Contac 12 Hour Allergy resources

• Contac 12 Hour Allergy Side Effects (in more detail)
• Contac 12 Hour Allergy Use in Pregnancy & Breastfeeding
• Contac 12 Hour Allergy Drug Interactions
• Contac 12 Hour Allergy Support Group
• 0 Reviews for Contac2 Hour Allergy - Add your own review/rating

• Clemastine Prescribing Information (FDA)


• Allerhist-1 MedFacts Consumer Leaflet (Wolters Kluwer)


• Clemastine Fumarate Monograph (AHFS DI)


• Tavist Consumer Overview

Compare Contac 12 Hour Allergy with other medications

• Allergic Reactions
• Hay Fever
• Urticaria

Where can I get more information?

• Your pharmacist has more information about clemastine written for health professionals that you may read.

See also: Contac2 Hour Allergy side effects (in more detail)

Northstar Rx

Address Northstar Rx, 4971 Southridge Blvd. Suite 101 Memphis TN 38141 Contact Details Phone: 1-800-206-7821 Website: http://www.northstarrxllc.com/

Codeine/Guaifenesin Liquid

Pronunciation: KOE-deen/gwye-FEN-e-sin
Generic Name: Codeine/Guaifenesin
Brand Name: Examples include Guiatuss AC and Tussi-Organidin NR

Codeine/Guaifenesin Liquid is used for:

Relieving cough and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Codeine/Guaifenesin Liquid is a cough suppressant and expectorant combination. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough. The expectorant works by loosening mucus and lung secretions in the chest and making coughs more productive.

Do NOT use Codeine/Guaifenesin Liquid if:

• you are allergic to any ingredient in Codeine/Guaifenesin Liquid or any other codeine- or morphine-related medicine (eg, oxycodone)


• you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)


• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Codeine/Guaifenesin Liquid:

Some medical conditions may interact with Codeine/Guaifenesin Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to morphine, codeine, or any other opiate (eg, hydrocodone, dihydrocodeine, oxycodone)


• if you have a history of an enlarged prostate gland or other prostate problems, heart problems, kidney or liver problems, a blockage of your bowel or bladder, adrenal gland problems (eg, Addison disease), or an underactive thyroid


• if you have a history of stomach problems, bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent abdominal surgery


• if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus


• if you have recently had any head injury, brain injury or tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures


• if you have a history of alcohol abuse, drug abuse, or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with Codeine/Guaifenesin Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• HIV protease inhibitors (eg, ritonavir) because the risk of side effects from Codeine/Guaifenesin Liquid may be increased


• Cimetidine, digoxin, droxidopa, or sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, seizures, irregular heartbeat, or heart attack may be increased


• Naltrexone or quinidine because the effectiveness of Codeine/Guaifenesin Liquid may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Codeine/Guaifenesin Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Codeine/Guaifenesin Liquid:

Use Codeine/Guaifenesin Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Codeine/Guaifenesin Liquid by mouth with or without food.


• Drink plenty of water while taking Codeine/Guaifenesin Liquid.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Codeine/Guaifenesin Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Codeine/Guaifenesin Liquid.

Important safety information:

• Codeine/Guaifenesin Liquid may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Codeine/Guaifenesin Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.


• Codeine/Guaifenesin Liquid may interfere with certain lab test results. Make sure that your doctor and lab personnel know that you are taking Codeine/Guaifenesin Liquid.


• Tell your doctor or dentist that you take Codeine/Guaifenesin Liquid before you receive any medical or dental care, emergency care, or surgery.


• Use Codeine/Guaifenesin Liquid with caution in the ELDERLY; they may be more sensitive to its effects.


• Caution is advised when using Codeine/Guaifenesin Liquid in CHILDREN; they may be more sensitive to its effects.


• Codeine/Guaifenesin Liquid should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.


• If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Codeine/Guaifenesin Liquid while you are pregnant. It is not known if Codeine/Guaifenesin Liquid is found in breast milk. Do not breast-feed while taking Codeine/Guaifenesin Liquid.

Possible side effects of Codeine/Guaifenesin Liquid:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Codeine/Guaifenesin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Codeine/Guaifenesin Liquid:

Store Codeine/Guaifenesin Liquid at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Codeine/Guaifenesin Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about Codeine/Guaifenesin Liquid, please talk with your doctor, pharmacist, or other health care provider.


• Codeine/Guaifenesin Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Codeine/Guaifenesin Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Codeine/Guaifenesin resources

• Codeine/Guaifenesin Side Effects (in more detail)
• Codeine/Guaifenesin Use in Pregnancy & Breastfeeding
• Drug Images
• Codeine/Guaifenesin Drug Interactions
• Codeine/Guaifenesin Support Group
• 21 Reviews for Codeine/Guaifenesin - Add your own review/rating

Compare Codeine/Guaifenesin with other medications

• Cough

Cyclogest 200 and 400 mg

Cyclogest 200mg and 400mg

(progesterone)

Cyclogest is the registered trademark of L.D. COLLINS and CO., Limited

Read all of this leaflet carefully before you start taking this medicine.

• Keep this leaflet. You may need to read it again.


• If you have any further questions, ask your doctor or pharmacist.


• This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.

Index

• 
  1 What Cyclogest is and what it is used for
  


• 
  2 Before you use
  


• 
  3 How to use
  


• 
  4 Possible side effects
  


• 
  5 How to store
  


• 
  6 Further information
  

What Cyclogest is and what it is used for

Cyclogest contains progesterone which is a natural, female sex hormone, produced in the body. This medicine works by adjusting the hormonal balance within the body.

Cyclogest may be used for treating:

• pre-menstrual syndrome which often affects women during the 7 to 10 days before their monthly period. The symptoms
  of pre-menstrual syndrome include feelings of tension, irritability, depression, headache, breast tenderness, weight gain and bloatedness


• post-natal depression which some women get after their baby has been born.

Before you use

Do not use Cyclogest and tell your doctor if you:

• have ever had any unexpected and unexplained bleeding from your vagina which was not due to your normal monthly period.

Check with your doctor or pharmacist before using Cyclogest if you:

• ever had liver problems such as jaundice (yellowing of the skin and whites of the eyes).

Pregnancy and breast-feeding

If you are pregnant, think you may be pregnant, planning a family or breast-feeding, ask your doctor or pharmacist for advice before using this medicines.

How to use

Always use Cyclogest exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist.

Do not swallow Cyclogest.

The usual dose is 200mg once a day or 400mg twice a day by vaginal or rectal insertion.

For premenstrual tension start using Cyclogest on day 12 or 14 of your menstrual cycle. This can be planned and marked onto your calendar, day 1 is the first day of your monthly period, counting forward to day 12 or 14 as advised by your doctor.

The pessary may be inserted into either the vagina or rectum (back passage) depending upon the following certain other conditions. You should insert Cyclogest into the:

• 
  vagina if you have:
  
  
  • colitis (inflammation of the colon causing frequent attacks of diarrhoea with mucous or blood)
  • problems controlling your bowel movements (faecal incontinence).


• 
  rectum (back passage) if you have:
  
  
  • a vaginal infection (discharge from your vagina)
  • or often have cystitis (a burning pain on passing water)
  • recently given birth
  • to use a barrier method of birth control such as a diaphragm, cap or condom. Such devices may not work properly in the presence of the vegetable fat from the pessary.

How to insert Cyclogest

Always wash your hands before and after inserting the pessary.

To insert into the:

• 
  Vagina - place the pessary between the lips of the vagina and push the pessary upwards and backwards. You may find it easier to do this if you are lying down or squatting.


• 
  Rectum (back passage) - gently push the pessary into the rectum for about one inch.

Your muscles will hold the pessary in place when it is in far enough. Squeeze your buttocks together for a few seconds.

If you use more Cyclogest than you should

If you (or someone else) has accidentally swallowed any of the pessaries or you use too many, contact your nearest hospital casualty department or your doctor immediately for advice.

If you miss a dose of Cyclogest

If you forget to insert a pessary, do so as soon as you remember, unless it is nearly time for the next dose. Never use two doses together. Remember to use the remaining doses at the correct time.

Possible side effects

Like all medicines, Cyclogest can cause side effects, although not everybody gets them.

Tell your doctor if you notice any of the following side effects or notice any other effects not listed:

• diarrhoea


• soreness in your rectum (back passage)


• flatulence (wind).

Do not worry if you find changes in your menstrual cycle. You may find that your monthly period will start earlier than usual or it may be delayed.

After using Cyclogest you may notice some leakage after the pessary has dissolved. Do not worry, this is quite normal when using medicines that are inserted into the vagina or rectum.

If you notice any side effects, they get worse, or if you notice any not listed, please tell your doctor or pharmacist.

How to store

Keep out of the reach and sight of children.

Store below 25°C in a dry place.

Do not use Cyclogest after the expiry date stated on the label/carton/bottle. The expiry date refers to the last day of that month.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Further information

What Cyclogest contains

• The active substance (the ingredient that makes the tablets work) is progesterone. Each pessary contains either 200mg or 400mg of the active ingredient.


• The other ingredients are vegetable fat.

What Cyclogest looks like and contents of the pack

Cyclogest are off-white pessaries.

Pack sizes are 15.

Marketing Authorisation Holder and manufacturer

Actavis

Barnstaple

EX32 8NS

UK

This leaflet was last revised in June 2009

Premenstrual Syndrome

Many women suffer from a condition called premenstrual syndrome or PMS. This is commonly known as PMT (premenstrual tension) because of the anxiety and bad temper often associated with it. However, there are many other symptoms that occur with PMS including depression, bloating and breast tenderness. It is not just your symptoms that decide whether you have PMS but the time at which they are at their worst.

PMS is characterised by the symptoms that occur during the days leading up to your period and are then completely relieved by menstruation. The cause of PMS is not completely understood but it is believed to be related to the hormonal changes that occur during the monthly cycle. Many women obtain relief from their symptoms when their hormonal balance is altered with a medicine prescribed by their doctor.

Further information about PMS can be obtained from:

National Association for Premenstrual Syndrome

41 Old Road

East Peckham

Kent

TN12 5AP

Post-Natal Depression

Many mothers experience short-term periods of mild depression following the birth of their baby. This is a common condition, usually occurring three or four days after delivery, affecting at least half of all new mothers who may feel tearful, overwhelmed and irritable during this time. Support, reassurance and rest can help these feelings to pass within a few days.

However, if the anxiety does not improve, the mother may be developing postnatal depression. Up to 15 per cent of new mothers develop more severe symptoms within 12 months of their child’s birth. Postnatal depression (PND) is characterised by marked low mood for a more prolonged period of time.

Though it may take several weeks or months until a full recovery is reached, PND is a treatable condition from which the mother will get better.

Speak to your midwife, health visitor or doctor if you have any further questions.

If you would like a leaflet with larger text, please contact 01271 311257.

Actavis

Barnstaple

EX32 8NS

UK

50213101

Nitrogen

Dosage Form: gas
Nitrogen

Nitrogen, Refrigerated Liquid

UN1977

CAS 7727-37-9

NON-FLAMMABLE GAS 2


Nitrogen, NF


ALWAYS KEEP CONTAINER IN UPRIGHT POSITION

DO NOT CHANGE OR FORCE FIT CONNECTIONS.


WARNING:     EXTREMELY COLD LIQUID AND GAS UNDER PRESSURE.

    CAN CAUSE RAPID SUFFOCATION.

                        CAN CAUSE SEVERE FROSTBITE.  

    Store and use with adequate ventilation.

    Do not get liquid in eyes, on skin or clothing.

    For liquid withdrawal, wear face shield and gloves.

    Do not drop. Use hand truck for container movement.

                       Container temperature should not exceed 52oC(125oF).

    Close valve after each use and when empty.

                       Use a back flow preventive device in the piping.

    Use in accordance with Material Safety Data Sheet.

    

 FIRST AID:   IF INHALED, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.


    IN CASE OF FROSTBITE, obtain medical treatment immediately.


    Rx Only

WARNING:     Administration of Nitrogen may be hazardous or contraindicated. For use by or under the supervision of a licensed practitioner who is experienced in the use and administration of Nitrogen and is familiar with the indications, effects, dosages, methods, and frequency and duration of administration, and with the hazards, contraindications and side effects, and the precautions to be taken.    

    

DO NOT REMOVE THIS LABEL.

            

A and B Welding Supply Co. Inc.

605-343-5365

914 East Chicago Street

PO Box 2053

Rapid City, SD  57709            Contents:

FILLED AND DISTRIBUTED BY:

A AND B WELDING SUPPLY CO., INC

914 E CHICAGO ST

RAPID CITY, SD  57701

605-343-5365

Nitrogen, REFRIGERATED LIQUID NF

UN 1977

NON-FLAMMABLE GAS 2

ALWAYS KEEP CONTAINER IN UPRIGHT POSITION

DO NOT CHANGE OR FORCE FIT CONNECTIONS

Rx only. WARNING: Administration of Nitrogen my be hazardous or contraindicated. For use only by or under the supervision of a licensed practitioner who is experienced in the use and administration of Nitrogen and is familiar with the indications, effects, dosages, methods, and frequency and duration of administration, and with the hazards, contraindications and side effects and the precautions to be taken.

WARNING: EXTREMELY COLD LIQUID AND GAS UNDER PRESSURE. CAN CAUSE RAPID SUFFOCATION. CAN CAUSE SEVERE FROSTBITE. Store and use with adequate ventilation. Do not get liquid in eyes, on skin or clothing. For liquid withdrawal, wear face shield and gloves. Do not drop. Use suitable hand truck for container movement. cylinder temperature should not exceed 52 degrees C (125 degrees F). Close valve after each use and when empty. Use a back flow preventive device in the piping. Use in accordance with the Material Safety Data Sheet (MSDS).

FIRST AID: IF INHALED, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give Oxygen. Call a physician. IN CASE OF FROSTBITE, obtain medical treatment immediately. CAS 7727-37-9

Nitrogen  Nitrogen  gas

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 55728-002 Route of Administration RESPIRATORY (INHALATION) DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Nitrogen (Nitrogen) Nitrogen 990 mL  in 1 L

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 55728-002-01 5 L In 1 CYLINDER None 2 55728-002-02 10 L In 1 CYLINDER None 3 55728-002-03 18 L In 1 CYLINDER None 4 55728-002-04 20 L In 1 CYLINDER None 5 55728-002-05 160 L In 1 DEWAR None 6 55728-002-06 180 L In 1 DEWAR None 7 55728-002-07 200 L In 1 DEWAR None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved medical gas		01/09/2012

Labeler - A & B Welding Supply Co. (007499460)

Establishment
Name	Address	ID/FEI	Operations
A & B Welding Supply Co.		007499460	manufacture

Revised: 01/2012A & B Welding Supply Co.

Imigran

Imigran may be available in the countries listed below.

UK matches:

• Imigran 10mg and 20mg Nasal Spray (SPC)
• Imigran Radis 50mg and 100mg Tablets (SPC)
• Imigran Recovery (SPC)

Ingredient matches for Imigran

Sumatriptan

Sumatriptan is reported as an ingredient of Imigran in the following countries:

• Austria


• Bosnia & Herzegowina


• Brazil


• Chile


• Colombia


• Croatia (Hrvatska)


• Czech Republic


• Denmark


• Estonia


• Finland


• Germany


• Greece


• Hungary


• Ireland


• Italy


• Japan


• Oman


• Romania


• Russian Federation


• Serbia


• Slovakia


• South Africa


• Sweden


• Switzerland


• Tunisia


• Turkey


• United Kingdom

Sumatriptan succinate (a derivative of Sumatriptan) is reported as an ingredient of Imigran in the following countries:

• Australia


• Austria


• Bahrain


• Brazil


• Bulgaria


• Chile


• Colombia


• Costa Rica


• Croatia (Hrvatska)


• Cyprus


• Czech Republic


• Denmark


• Estonia


• Finland


• Georgia


• Germany


• Greece


• Guyana


• Hong Kong


• Hungary


• Iceland


• Iran


• Ireland


• Italy


• Jordan


• Kuwait


• Latvia


• Lebanon


• Lithuania


• Malaysia


• Malta


• Mexico


• Netherlands


• New Zealand


• Norway


• Oman


• Peru


• Philippines


• Poland


• Portugal


• Qatar


• Romania


• Russian Federation


• Serbia


• Singapore


• Slovakia


• Slovenia


• Spain


• Sri Lanka


• Sweden


• Switzerland


• Syria


• Taiwan


• Thailand


• United Arab Emirates


• United Kingdom


• Venezuela


• Yemen

International Drug Name Search

Glossary

SPC	Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

AK-Sulf

Generic Name: sulfacetamide ophthalmic (SUL fa SEET a mide off THAL mik)

Brand Names: Bleph-10, Ocu-Sul 10, Ocu-Sul 15, Ocu-Sul 30, Sodium Sulamyd, Sulf-10, Sulfac 10%

What is AK-Sulf (sulfacetamide ophthalmic)?

Sulfacetamide ophthalmic is an antibiotic.

Sulfacetamide ophthalmic is used to treat bacterial infections of the eyes.

Sulfacetamide ophthalmic may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about AK-Sulf (sulfacetamide ophthalmic)?

Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye.

Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear ducts.

Who should not use AK-Sulf (sulfacetamide ophthalmic)?

Do not use sulfacetamide ophthalmic if you have a viral or fungal infection in your eye. It is used to treat infections caused by bacteria only.

Do not use sulfacetamide ophthalmic if you have ever had an allergic reaction to a sulfa-based drug.

It is not known whether sulfacetamide ophthalmic will harm an unborn baby. Do not use sulfacetamide ophthalmic without first talking to your doctor if you are pregnant. It is also not known whether sulfacetamide ophthalmic passes into breast milk. Do not use sulfacetamide ophthalmic without first talking to your doctor if you are breast-feeding a baby.

How should I use AK-Sulf (sulfacetamide ophthalmic)?

Use sulfacetamide ophthalmic eyedrops or ointment exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before using your eyedrops or ointment.

To apply the eye drops:

• 
  

  Shake the drops gently to be sure the medicine is well mixed. Tilt your head back slightly and pull down on your lower eyelid. Position the dropper above your eye. Look up and away from the dropper. Squeeze out a drop and close your eye. Apply gentle pressure to the inside corner of your eye (near your nose) for about 1 minute to prevent the liquid from draining down your tear duct. If you are using more than one drop in the same eye or drops in both eyes, repeat the process with about 5 minutes between drops.

  
  

To apply the ointment:

• 
  

  Hold the tube in your hand for a few minutes to warm it up so that the ointment comes out easily. Tilt your head back slightly and pull down gently on your lower eyelid. Apply a thin film of the ointment into your lower eyelid. Close your eye and roll your eyeball around in all directions for 1 to 2 minutes. If you are applying another eye medication, allow at least 10 minutes before the next application.

  
  

Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye. Do not use any eyedrop that is discolored or has particles in it. Store sulfacetamide ophthalmic at room temperature away from moisture and heat. Keep the bottle or tube properly capped.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.

What happens if I overdose?

An overdose of this medication is unlikely to occur. If you do suspect an overdose, wash the eye with water and call an emergency room or poison control center near you. If the drops or ointment have been ingested, drink plenty of fluid and call an emergency center for advice.

What should I avoid while using AK-Sulf (sulfacetamide ophthalmic)?

Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye. Use caution when driving, operating machinery, or performing other hazardous activities. Sulfacetamide ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities.

If you wear contact lenses, ask your doctor if you should wear them during treatment with sulfacetamide ophthalmic. After applying the medication, wait at least 15 minutes before inserting contact lenses, unless otherwise directed by your doctor.

Do not use other eye drops or medications during treatment with sulfacetamide ophthalmic unless otherwise directed by your doctor.

AK-Sulf (sulfacetamide ophthalmic) side effects

Serious side effects are not expected with this medication.

Commonly, some eye burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect AK-Sulf (sulfacetamide ophthalmic)?

Do not use this medication with other eyedrops containing nitrates (e.g., silver nitrate).

Do not use other eye drops or medications during treatment with sulfacetamide ophthalmic unless otherwise directed by your doctor.

Drugs other than those listed here may also interact with sulfacetamide ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More AK-Sulf resources

• AK-Sulf Side Effects (in more detail)
• AK-Sulf Use in Pregnancy & Breastfeeding
• AK-Sulf Drug Interactions
• AK-Sulf Support Group
• 0 Reviews for AK-Sulf - Add your own review/rating

• Bleph-10 Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Bleph-10 Prescribing Information (FDA)


• Isopto Cetamide Prescribing Information (FDA)

Compare AK-Sulf with other medications

• Conjunctivitis
• Trachoma

Where can I get more information?

• Your pharmacist has additional information about sulfacetamide ophthalmic written for health professionals that you may read.

See also: AK-Sulf side effects (in more detail)

Ifistatin

Ifistatin may be available in the countries listed below.

Ingredient matches for Ifistatin

Simvastatin

Simvastatin is reported as an ingredient of Ifistatin in the following countries:

• Singapore


• Sri Lanka

International Drug Name Search

Selseb Topical

Generic Name: selenium sulfide (Topical route)

se-LEE-nee-um SUL-fide

Commonly used brand name(s)

In the U.S.

• Dandrex


• Selenos


• Selseb


• Selsun Blue Medicated Treatment


• Tersi Foam

In Canada

• Versel

Available Dosage Forms:

• Lotion


• Cream


• Shampoo


• Foam


• Suspension

Therapeutic Class: Antiseborrheic

Uses For Selseb

Selenium sulfide 1% and 2.5% strengths are used on the scalp to help control the symptoms of dandruff and seborrheic dermatitis.

Selenium sulfide 2.5% strength is used also on the body to treat tinea versicolor (a type of fungus infection of the skin).

In the United States, the 2.5% strength is available only with your doctor's prescription.

Before Using Selseb

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing use of selenium sulfide in infants and children with use in other age groups; however, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of selenium sulfide in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Blistered, raw, or oozing areas on your scalp or body—Use of this medicine on these areas may increase the chance of absorption through the skin

Proper Use of selenium sulfide

This section provides information on the proper use of a number of products that contain selenium sulfide. It may not be specific to Selseb. Please read with care.

If you are using the 2.5% strength of selenium sulfide: Use this medicine only as directed. Do not use it more often than recommended on the label, unless otherwise directed by your doctor.

If you are using the 1% strength of selenium sulfide : For best results, use this medicine at least 2 times a week or as directed by your doctor.

To use selenium sulfide for dandruff or seborrheic dermatitis of the scalp:

• Before using this medicine, wet the hair and scalp with lukewarm water.


• Apply enough medicine (1 or 2 teaspoonfuls) to the scalp to work up a lather. Allow the lather to remain on the scalp for 2 to 3 minutes, then rinse.


• Apply the medicine again and rinse well.


• If this medicine is used on light or blond, gray, or chemically treated (bleached, tinted, permanent-waved) hair, rinse your hair well for at least 5 minutes after using the medicine to lessen the chance of hair discoloration.


• After treatment, wash your hands well.

To use selenium sulfide for tinea versicolor of the body:

• Apply the medicine to the affected areas of your body, except for your face and genitals (sex organs).


• Work up a lather using a small amount of water.


• Allow the medicine to remain on your skin for 10 minutes.


• Rinse your body well to remove all the medicine.

Do not use this medicine if blistered, raw, or oozing areas are present on your scalp or the area of your body that is to be treated , unless otherwise directed by your doctor.

Keep this medicine away from the eyes. If you should accidentally get some in your eyes, flush them thoroughly with water.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For lotion dosage form:
  
  • For dandruff or seborrheic dermatitis:
    
    • Adults and children—If you are using the 1% lotion, use on the scalp two times a week. If you are using the 2.5% lotion, use on the scalp two times a week for two weeks, then use one time a week or less often.
    
    
    • Infants—Use and dose must be determined by your doctor.
    
    
  
  
  • For tinea versicolor:
    
    • Adults and children—Use the 2.5% lotion on the body one time a day for seven days.
    
    
    • Infants—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Selseb

If your condition does not get better after regular use of this medicine, or if it gets worse, check with your doctor.

Selseb Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

• Skin irritation

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Unusual dryness or oiliness of hair or scalp

Less common

• Increase in normal hair loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Selseb Topical side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Selseb Topical resources

• Selseb Topical Side Effects (in more detail)
• Selseb Topical Use in Pregnancy & Breastfeeding
• Selseb Topical Support Group
• 0 Reviews for Selseb Topical - Add your own review/rating

Compare Selseb Topical with other medications

• Seborrheic Dermatitis
• Tinea Versicolor

Chloroxylenol/Benzocaine/Hydrocortisone Drops

Pronunciation: KLOR-oh-ZYE-le-nol/BEN-zoe-kane/HYE-droe-KOR-ti-sone
Generic Name: Chloroxylenol/Benzocaine/Hydrocortisone
Brand Name: Trioxin

Chloroxylenol/Benzocaine/Hydrocortisone Drops are used for:

Treating certain infections of the outer ear canal that occur with inflammation. It is also used to control itching of the ear canal.

Chloroxylenol/Benzocaine/Hydrocortisone Drops are an antibacterial and antifungal, steroid, and anesthetic combination. It works by killing bacteria, reducing inflammation, and temporarily relieving itching and pain.

Do NOT use Chloroxylenol/Benzocaine/Hydrocortisone Drops if:

• you are allergic to any ingredient in Chloroxylenol/Benzocaine/Hydrocortisone Drops


• you have chickenpox or vaccinia viral infection


• your eardrum is perforated

Contact your doctor or health care provider right away if any of these apply to you.

Before using Chloroxylenol/Benzocaine/Hydrocortisone Drops:

Some medical conditions may interact with Chloroxylenol/Benzocaine/Hydrocortisone Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you are allergic to other local anesthetics (eg, tetracaine)

Some MEDICINES MAY INTERACT with Chloroxylenol/Benzocaine/Hydrocortisone Drops. Because little, if any, of Chloroxylenol/Benzocaine/Hydrocortisone Drops are absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Chloroxylenol/Benzocaine/Hydrocortisone Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Chloroxylenol/Benzocaine/Hydrocortisone Drops:

Use Chloroxylenol/Benzocaine/Hydrocortisone Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Chloroxylenol/Benzocaine/Hydrocortisone Drops are only for the ear. Do not get it in your eyes, nose, or mouth. If you get Chloroxylenol/Benzocaine/Hydrocortisone Drops in any of these areas, rinse right away with cool water.


• Thoroughly clean and dry the outer ear before using Chloroxylenol/Benzocaine/Hydrocortisone Drops.


• Wash your hands before and after using Chloroxylenol/Benzocaine/Hydrocortisone Drops.


• Shake well before each use.


• Lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for 5 minutes so the medicine can run to the bottom of the ear canal. A clean cotton plug may be gently inserted into the ear canal to prevent medicine from leaking out.


• To prevent germs from getting into your medicine, do not touch the applicator to any surface, including the ear. Keep the container tightly closed.


• To clear up your infection completely, keep using Chloroxylenol/Benzocaine/Hydrocortisone Drops for the full course of treatment. Keep using it even if your condition improves in a few days.


• If you miss a dose of Chloroxylenol/Benzocaine/Hydrocortisone Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Chloroxylenol/Benzocaine/Hydrocortisone Drops.

Important safety information:

• Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.


• Be sure to use Chloroxylenol/Benzocaine/Hydrocortisone Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria or fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.


• Long-term or repeated use of Chloroxylenol/Benzocaine/Hydrocortisone Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.


• Do not use Chloroxylenol/Benzocaine/Hydrocortisone Drops for other ear infections or conditions without checking with your doctor.


• Chloroxylenol/Benzocaine/Hydrocortisone Drops may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Chloroxylenol/Benzocaine/Hydrocortisone Drops while you are pregnant. It is not known if Chloroxylenol/Benzocaine/Hydrocortisone Drops are found in breast milk. If you are or will be breast-feeding while you use Chloroxylenol/Benzocaine/Hydrocortisone Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Chloroxylenol/Benzocaine/Hydrocortisone Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, cracking, irritation, or peeling not present before you began using Chloroxylenol/Benzocaine/Hydrocortisone Drops.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include acne-like rash; excessive hair growth; inflamed hair follicles; inflammation around the mouth; muscle weakness; thinning, softening, discoloration, or stretch-like appearance of the skin around the application site; unusual weakness; unusual weight gain, especially in the face.

Proper storage of Chloroxylenol/Benzocaine/Hydrocortisone Drops:

Store Chloroxylenol/Benzocaine/Hydrocortisone Drops between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Keep Chloroxylenol/Benzocaine/Hydrocortisone Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Chloroxylenol/Benzocaine/Hydrocortisone Drops, please talk with your doctor, pharmacist, or other health care provider.


• Chloroxylenol/Benzocaine/Hydrocortisone Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Chloroxylenol/Benzocaine/Hydrocortisone Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Chloroxylenol/Benzocaine/Hydrocortisone resources

• Chloroxylenol/Benzocaine/Hydrocortisone Use in Pregnancy & Breastfeeding
• Chloroxylenol/Benzocaine/Hydrocortisone Support Group
• 0 Reviews for Chloroxylenol/Benzocaine/Hydrocortisone - Add your own review/rating

Compare Chloroxylenol/Benzocaine/Hydrocortisone with other medications

• Otitis Externa

Methadone Concentrate

Pronunciation: METH-a-done
Generic Name: Methadone
Brand Name: Methadose

Methadone Concentrate may cause severe and sometimes fatal heart and breathing problems. These problems may occur some time after you take a dose. Tell your doctor right away if you develop any new or worsening symptoms such as slowed or shallow breathing or irregular heartbeat. Your doctor will perform heart and lung function tests to check for side effects while you take Methadone Concentrate. Keep all doctor and laboratory appointments. Talk with your doctor and be sure you understand the risks and benefits of using Methadone Concentrate.

Do not take more than the recommended dose or take Methadone Concentrate more often than prescribed. This can lead to overdose and possible death.

Methadone Concentrate is used for:

Treating a narcotic addiction as part of a treatment program. It may also be used for other conditions as determined by your doctor.

Methadone Concentrate is a narcotic analgesic. It works by acting on opiate pain receptors in the brain and on smooth muscle to provide pain relief.

Do NOT use Methadone Concentrate if:

• you are allergic to any ingredient in Methadone Concentrate


• you have slowed breathing or severe asthma, or if you are having an asthma attack


• you have a stomach or bowel blockage or certain severe bowel problems (eg, paralytic ileus)


• you have diarrhea caused by food poisoning or antibiotic use


• you are taking sodium oxybate (GHB)


• if you have taken a monamine oxidase inhibitor type B (MAOI-B) (eg, rasagiline, selegiline) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Methadone Concentrate:

Some medical conditions may interact with Methadone Concentrate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have lung or breathing problems (eg, asthma), chronic obstructive pulmonary disease (COPD), sleep apnea, stomach or bowel problems (eg, bowel inflammation), stomach pain or constipation, liver or kidney problems, thyroid problems, or Addison disease


• if you have an abnormal curvature of the spine; narrowing of the urethra, trouble urinating, or an enlarged prostate; low blood volume, blood pressure, or blood oxygen levels; low potassium or magnesium blood levels; increased pressure, tumors, or lesions in your head; a recent head injury; or seizures


• if you have a history of heart problems (eg, enlarged heart) or irregular heartbeat


• if you or a family member have a history of mental or mood problems (eg, anxiety, depression), suicidal thoughts or attempts, or alcohol or substance abuse


• if you are elderly, very ill, or very overweight, or if you have recently had stomach or intestine surgery

Some MEDICINES MAY INTERACT with Methadone Concentrate. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturate anesthetics (eg, thiopental), benzodiazepines (eg, midazolam), cimetidine, MAOI-B (eg, rasagiline, selegiline), other narcotic analgesics (eg, morphine), phenothiazines (eg, promethazine), or sodium oxybate (GHB) because side effects such as sedation and slowed breathing may occur


• Antiarrhythmics (eg, amiodarone, dofetilide, flecainide, propafenone), antipsychotics (eg, haloperidol, paliperidone, ziprasidone), calcium channel blockers (eg, nifedipine), certain antiemetics (eg, dolasetron, droperidol), chloroquine, cisapride, diuretics (eg, furosemide), H₁ antagonists (eg, astemizole), kinase inhibitors (eg, lapatinib, nilotinib), lithium, macrolide antibiotics (eg, clarithromycin), phenothiazines (eg, chlorpromazine), quinolones (eg, ciprofloxacin), streptogramins (eg, quinupristin), tacrolimus, or tricyclic antidepressants (eg, desipramine) because the risk of QT prolongation may be increased


• Azole antifungals (eg, fluconazole, ketoconazole, voriconazole) or certain selective serotonin reuptake inhibitors (SSRIs) (eg, fluvoxamine, sertraline) because they may increase the risk of Methadone Concentrate's side effects


• Abacavir, carbamazepine, efavirenz, HIV protease inhibitors (eg, amprenavir, lopinavir, nelfinavir, ritonavir), narcotic agonists/antagonists (eg, butorphanol, nalbuphine, pentazocine), narcotic antagonists (eg, naloxone, naltrexone), nevirapine, phenobarbital, phenytoin, rifampin, or St. John's wort because they may decrease Methadone Concentrate's effectiveness


• Zidovudine because the risk of its side effects may be increased by Methadone Concentrate


• Nucleoside reverse transcriptase inhibitors (NRTIs) (eg, abacavir, didanosine, stavudine) because their effectiveness may be decreased by Methadone Concentrate

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methadone Concentrate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Methadone Concentrate:

Use Methadone Concentrate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Methadone Concentrate by mouth with or without food. Methadone Concentrate is for oral use only and must not be injected.


• Methadone Concentrate must be administered under close medical supervision.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• Methadone Concentrate must be mixed with water or other liquid before you use it. Follow your doctor's instructions on how to mix Methadone Concentrate.


• Take Methadone Concentrate on a regular schedule to get the most benefit from it.


• If Methadone Concentrate is no longer needed, dispose of it as soon as possible. Ask your doctor or pharmacist how to dispose of Methadone Concentrate properly.


• Always keep Methadone Concentrate in a secure place to protect from theft.


• If you miss a dose of Methadone Concentrate and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you miss your doses of Methadone Concentrate for more than 2 days, contact your doctor before you start taking Methadone Concentrate again.

Ask your health care provider any questions you may have about how to use Methadone Concentrate.

Important safety information:

• Methadone Concentrate may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Methadone Concentrate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Methadone Concentrate; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Methadone Concentrate may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.


• Breathing problems may occur some time after you take a dose of Methadone Concentrate. Tell your doctor or seek medical care immediately if you notice trouble breathing (eg, slowed or shallow breathing) while you take Methadone Concentrate.


• Methadone Concentrate may cause constipation. Constipation may be avoided by using a stool softener or fiber laxative.


• The risk of Methadone Concentrate becoming habit-forming may be greater if you take it in high doses or for a long time. Do NOT take more than the recommended dose or use Methadone Concentrate for longer than prescribed without talking with your doctor.


• Tell your doctor or dentist that you take Methadone Concentrate before you receive any medical or dental care, emergency care, or surgery.


• Lab tests, including liver function, lung function, and heart function, may be performed while you use Methadone Concentrate. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Methadone Concentrate with caution in the ELDERLY; they may be more sensitive to its effects.


• Methadone Concentrate should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Methadone Concentrate may cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Methadone Concentrate while you are pregnant. Methadone Concentrate is found in breast milk. If you are or will be breast-feeding while you use Methadone Concentrate, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, Methadone Concentrate may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Methadone Concentrate stops working well. Do not take more than prescribed.

Some people who use Methadone Concentrate for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.

If you stop taking Methadone Concentrate suddenly, you may have WITHDRAWAL symptoms. These may include convulsions, tremor, stomach and muscle cramps, vomiting, and sweating. Do not stop therapy suddenly or change the dosage without asking your doctor. Discuss overuse with your doctor or pharmacist.

Possible side effects of Methadone Concentrate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth; headache; increased sweating; itching; lightheadedness; nausea; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; decreased sexual desire or ability; excessive drowsiness; fainting; fast, slow, or irregular heartbeat; hallucinations; loss of appetite; menstrual changes; mental or mood changes (eg, agitation, disorientation, exaggerated sense of well-being); seizures; severe or persistent dizziness or lightheadedness; shortness of breath; slow or shallow breathing; swelling of the arms, feet, or legs; trouble sleeping; trouble urinating; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Methadone side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include cold and clammy skin; coma; fainting; fast, slow, or irregular heartbeat; muscle weakness; pinpoint pupils; severe dizziness, drowsiness, or lightheadedness; slow, shallow, or difficult breathing.

Proper storage of Methadone Concentrate:

Store Methadone Concentrate at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Methadone Concentrate out of the reach of children and away from pets.

General information:

• If you have any questions about Methadone Concentrate, please talk with your doctor, pharmacist, or other health care provider.


• Methadone Concentrate is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Methadone Concentrate. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

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